complement activation

Dietary resistant starch enhances immune health of the kidney in diabetes via promoting microbially-derived metabolites and dampening neutrophil recruitment

Background: Dietary-resistant starch is emerging as a potential therapeutic tool to limit the negative effects of diabetes on the kidneys. However, its metabolic and immunomodulatory effects have not yet been fully elucidated. Methods: Six-week-old …

The Complement Pathway: New Insights into Immunometabolic Signaling in Diabetic Kidney Disease

The metabolic disorder, diabetes mellitus, results in microvascular complications, including diabetic kidney disease (DKD), which is partly believe to involve disrupted energy generation in the kidney, leading to injury that is characterized by …

Complement C5a Induces Renal Injury in Diabetic Kidney Disease Via Disruption in Mitochondrial Metabolic Agility

The sequelae of diabetes mellitus include microvascular complications such as diabetic kidney disease (DKD), which involves glucose-mediated renal injury that is associated with a disruption in mitochondrial metabolic agility, inflammation and …

Resistant starch is protective against diabetic nephropathy by inhibition of complement activation in a mouse model of diabetes

Nutrition Society of Australia 43rd Annual Scientific Meeting

Dietary Resistant Starch Protects Against Diabetic Nephropathy by Inhibition of Complement

54th Australian and New Zealand Society of Nephrology Annual Scientific Meeting